After sphere info missing, the calibration did not work any more. Help needed.

In the settings for a qualification sphere there is a size. This has to be set to the size of the sphere you are using. That should be a calibrated (traceable to NIST here in the U.S.) number you know to a lot of decimal places.
This is the function that lets the CMM determine what size things are when using multiple "sides" of the stylus, like measuring across a circle or walls on a slot.

If the diameter is REALLY off, it could miss on the hits trying to find the sphere.

I don't know what controller you are on, but on some, if the turtle button is not hot on the jog box, the machine won't compensate for the hit. This would make it not retract (I beleive) and also make the machine think the sphere is somewhere on Z that it isn't, making subsequent hits miss the sphere.

With the limitted info available, I'd suggest starting with those two items. Get the diameter correct (the vector for the stem is important too, but not the problem you are describing at the moment), and make sure your hit is right.

Calibrate with five manual hits (in the buttons in teh cal window select MAN not DCC+DCC, just MAN). Does that get you results?

Can you qualify the position you do manually in DCC+DCC AFTER doing it manually?

I don't think you have a hardware issue, I could be wrong, but this sounds like a human made situation, based on the information available to me at this time.

In the settings for a qualification sphere there is a size. This has to be set to the size of the sphere you are using. That should be a calibrated (traceable to NIST here in the U.S.) number you know to a lot of decimal places.
This is the function that lets the CMM determine what size things are when using multiple "sides" of the stylus, like measuring across a circle or walls on a slot.

If the diameter is REALLY off, it could miss on the hits trying to find the sphere.

I don't know what controller you are on, but on some, if the turtle button is not hot on the jog box, the machine won't compensate for the hit. This would make it not retract (I beleive) and also make the machine think the sphere is somewhere on Z that it isn't, making subsequent hits miss the sphere.

With the limitted info available, I'd suggest starting with those two items. Get the diameter correct (the vector for the stem is important too, but not the problem you are describing at the moment), and make sure your hit is right.

Calibrate with five manual hits (in the buttons in teh cal window select MAN not DCC+DCC, just MAN). Does that get you results?

Can you qualify the position you do manually in DCC+DCC AFTER doing it manually?

I don't think you have a hardware issue, I could be wrong, but this sounds like a human made situation, based on the information available to me at this time.