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Changes to Machine Interface Setup not being saved

I am running PC DMIS 2023.2 on a new machine. I am trying to make changes to the Machine Interface Setup. It allows me to apply these changes, set them to default etc. 

When I close the menu and re-open the menu my changes are still there, but if I close and re-open PC-DMIS my changes are undone and they are back to default.

Additionally, if I open the settings editor, the values I adjusted are set to what I adjusted them to, even though PC-DMIS is displaying the default values.

Is there any reason my settings in my settings editor and my settings in my user interface setup in PC-DMIS would not relate correctly? 

Is it possible this is a registry editor permissions issue?

Is there a way for me to adjust these values in the actual file that they should be writing to?

Thanks in advance for any help.