1. If you have stress vs strain data, then you have to create a table for True stress vs True plastic strain data. Then refer the table which is function of "eq_plastic_strain". The first point in the table should be zero plastic strain and yield stress. If you use this data, then you can set Yield Stress as 1, since the loading will follow the true stress vs true plastic strain data.
2. Yes, yield stress can be made a function of temperature also. Here in this case, you must create a two independent variable table which is a function of equivalent plastic strain and temperature.
3. Since the stresses do not shift in Isotropic hardening, the isotropic hardening constant and it is set to "0". If you want to vary the hardening, then you have to use Kinematic or Combined hardening.
Please go through the document attached from MAR101.